THE HUMAN MICROBIOME: A New Frontier in Health
Microbiome expands the genetic and functional capacity of its human host. Susan Lynch explains that human microbiome develops early in life and that gut microbes shape immune function and relate to disease outcomes in childhood. She also explores next-generation microbiome therapeutics and research. Recorded on 11/07/2019. [12/2019] [Show ID: 35240]
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0:00 Introduction
0:49 What We'll Cover Tonight.....
2:06 Microbes Pre-date Earth's Biodiversity
3:23 Culture-based Approaches do not Reflect the True Diversity or Physiology of Microorganisms
8:00 Enabling Tools to Interrogate Microbial Dark Matter
10:11 Humans are Superorganisms
11:12 The Gut Microbiome is Home to Several Trillion Microbes
12:22 Genetic Capacity of the Gut Microbiome Dwarfs that of the Human Host
13:48 The Gut Microbiome Evolves Over Human Lifespan
16:56 Human gut microbiome viewed across age and geography
19:07 Diet Rapidly and Reproducibly Alters the Gut Microbiome
21:52 Microbiome Perturbation Associates with Disease
22:38 The Gut Microbiome Influences Remote Organ and Immune Responses
23:47 Human Microbiome - a Lever on Host Physiology
25:58 Yellow Soup for the Soul!
30:55 Asthma is Prevalent in Westernized Nations
36:47 Gut Microbiome Manipulation Alters Airway Mucosal Response to Allergen Challenge or Viral Infection
38:18 Gut Microbiome Manipulation Alters Serum Metabolic Response to Viral Respiratory Infection
41:05 Gut Microbiome Influences Hematopoietic Cell Programing via Plasma-associated Mediators
42:52 How Could the Neonatal Gut Microbiome Influence Airway Disease Development in Childhood?
44:39 High-risk for Asthma Gut Microbiota is Distinct at Birth and Exhibits Delayed Development in Infancy
46:13 Wayne County Health, Environment, Allergy & Asthma Longitudinal Study (WHEALS) Birth cohort
47:04 Neonatal Gut Microbiota State is Associated with Risk of Childhood Atopy and Asthma
49:49 Human Immune Cell Assay to Assess Neonatal Gut Microbiome Immunostimulatory Capacity
50:46 High-risk Neonatal Gut Microbiome Induces Allergic Inflammation and Suppresses T-regulatory Cells
52:51 12,13 DIHOME Promotes Airway Allergic Sensitization and Increased Circulating IgE in Mice
54:09 Altered Linoleic Acid Metabolism Characterizes High-risk Gut Microbiota
55:17 Is the High-risk Neonatal Gut Microbiome Enriched for 12,13 DIHOME Production?
56:25 Neonatal Fecal 3EH Copy Number and 12,13 DIHOME Concentration Predicts Childhood Atopy and Asthma
57:33 Model for Childhood Atopic Asthma Development
59:40 Early-life Gut Microbiota Relates to Childhood Obesity and Overweight Phenotypes at 2 Years
Check out "Picky Eaters: Convincing Immune Cells to Eat Cancer" here: kzhead.info/sun/bJaFlcWdfmtsn5s/bejne.html
I'm a formula fed 70's child FUT2 non excretor. Suffered ADHD, numerous illnesses, addiction issues etc.. I'm finding health through organically growing my own vegetables with which to support my microbiome. Prolonged fasting has massively helped too as has cutting out alcohol, bread and vegetable fats. I make my own ferments and herbal extractions for digestive tonics. I fully subscribe to modulating your microbiome to help the physiology reach homeostasis.
...
I believe you are on the right path. Unfortunately most people for various reasons aren't in the position to grow their own foods.
WOW you should share what you have done too... so others liked me can learn! How do you make your own ferments and herbal extractions etc... Thanks
Q+q]
I need help ..very badly Mr hawail..... suffering from fear depression etc....pls suggest ferment i can adopt from india...
The speaker gave a fantastically well-organized and concise presentation! No off-topic rambling at all. This made it very easy to follow and stay focused on the information. Great job!
Yes, and no excess fluff, repetition to fill time, normal voice and clothes. I wish many others on KZhead would take note.
I received a FMT ( fecal microflora transplant) one month ago! I had a bacteria infection, took an antibiotic to get rid of it (C Diff bacteria)! I have no more C DIFF spores 🌝 Now that I have brand new gut bacteria, I am living ,and eating to feed THEM ❤ I feel like a new person mentally, physically, and spiritual!!!
Sulfite intake is directly linked to asthma symptoms and urticaria. Sulfites are ubiquitous, as they are used as a fumigant, antimicrobial agent and bleaching agent in the manufacturing/processing of foodstuffs. In the U.S. ingredients of ingredients are not required to be listed on food labels. So you won’t see sulfites listed when they are used in the processing of food raw materials. The worst offender is high fructose corn syrup (HFCS). Sulfites are used as antimicrobial “preservatives” in high fructose corn syrup at 1000 times the level permitted by the FDA as an additive, but as an ingredient of an ingredient, it need not be disclosed. Compounding this problem is the fact that many pediatricians tell parents of asthmatic children to replace milk with juice - often containing high fructose corn syrup, thus heavily laden with sulfites. Sulfites are also used as a bleaching agent in regular sugar, flour and salt. So condiments and gravy and other flour products can be a problem. Sulfites are also used in the manufacturing process of all alcoholic beverages and all sugared beverages. Additionally, sulfites are found in all frozen seafood, to prevent black spots. The food technology industry has been allowed to become insidious in renaming high fructose corn syrup and even changing the manufacturing process, making it more potent and requiring more sulfites. There is information available on the internet regarding the tested content of sulfites in foodstuffs and the renaming of HFCS. If you, or someone you know suffer from asthma it’s worth the effort to research. Most of this information regarding sulfites became known because previously, restaurants were allowed to sprinkle metabisulfite on salad bar foods, e.g., greens, veggies, fruit, etc., resulting in more than a few asthmatics having immediate lethal asthma attacks. HTH!
Thank u fore this. Me and my asthma wil read up on it
Åshild Steine : Happy to help - good luck and be vigilant in your research.
@@maltipaws5128 thanks for this information regarding sulfites. I didn't know that about frozen seafood! It's like a full time job trying to gather information on what is safe to eat. It really shouldn't be this way.
Word Girl: Yup, it shouldn’t be this hard and it shouldn’t be a friggin secret. Americans should all know just how damaging their “food” can be.
Beautiful. Thank you.
She is one of the best speakers I've ever heard. I can listen to her all day. Little bit of residual Irish brogue, but she's clearly been in SoCal for a long time. And doing great work!
I love her irish accent!
It's not about her it's about the content stop people worshiping
The message has a messenger...if it's Irish it carries a deep understanding of some things
@@africanqueenmo Growth in knowledge is an inspirational gift of God. Enjoy it and use it to the glory of God and the Good of humanity.
The good is to be praised.
As an infectious disease physician who has had an abiding interest in the health and disease implications of the human micro biome for several years, I almost skipped this presentation. So glad I didn’t! Great information, well-organized and communicated in a highly engaging and compelling manner.
How does fat solubility play into this.?
@@dowbrown4454 How do you think?
@@dowbrown4454 Welcome to the worldwide wireless concentration cramp ! maybe if we'd kiss our corporate cattlerancher state pharmer KINGPIMPS of gangstas pair-o-dice asses hard enough --- they might treat us a little better huh ? (Stockholm syndrome) We best start sharpening our mental shivs yawl. Hold fast (intermittent fasting from the poi-zion food and information supply) , and stay vigilant (meditation is prayer) --- to achieve Goddesspeed yawl. Time to conscientiously rip the goddamn blindfold MASK veil off Lady Justice --- so she can properly thrash that greedy-sadistic judiciously corrupt fraternity of pig-raping motherfrackers out of the equation entirely. . . We need to change "good mourning." into "good dawning !" REJOICE for the kingdom of heaven is in play ! FREEK-OUT ! And BIG Peace to all honest to goodness children of the earth ...
Being a woman who had two children first baby was formula after 6week developed allergy, s ear infections! Treatment with amoxicillin to the point he developed fungus infection in his sinuses and high white blood cells treated for fungus infections and the gut problems of pain gas I used anise tea and licorice for the stomach no doctor did anything for his tummy! He has always been heavy and still under treatment for alligerys baby 2 breast feed 4year s and healthy eating habits never sick he also has tree and grass allergies he has normal weight! He was a lamaze delivery no pain medication but both pregnancy I had toxemia put to bed 3 months last trimester! I have a heart murmur! Health person a thin woman great health and energy other wise! But allergy to mold spores! So I think this gut biome is key to health! My advice is mother's breast feed and be taught how the different stages of breast milk come not to clean the breast like my firstborn I was instructed to clean my hands with alcohol then you touch your breast it wrong! the second time I never did this clean hand ,s I donated tons of breast milk to hospital and laliche league 4 years the high fat content of the milk was amazing! Just real information
I'm not Typhoid Marry. I don't think I'll ever get another vaccine again unless tied up in a straight jacket by the authorities. I've had many in my 55yrs but once they started becoming mandatory, never again. They are likely the cause of many of my and other peoples autoimmune symptoms. Medical science is not an exact science like engineering and when they say they know, they are lying to you. Keep us informed and back off. People, you are participating in an ongoing experiment and the people in charge are corrupt taking care of their own self interests. Please start living life.
Very instructive presentation. This lady is gifted by such a harmonious voice and perfect diction that I would pay to listen to her reciting the content of the phone book.
settle down spaz
Funny, but it is true. Not a bunch of fillers or stalling for thought, and uhs, and so's.
Yes, extremely clear and concise. I wish everyone that did presentations had her skill.
One of THE BEST presentations on the impact of the human microbiome. She so clearly & concisely condenses this vital, newer field and its critical role in human health.
I have suffered from asthma all my life and have been doing everything I can to improve my lifestyle and diet to reduce my symptoms. This lecture is mind blowing and has completely changed my view on the disease. If there was ever an opportunity to take part in clinical trials I would jump at the chance. Until then the new topic of study is gut biome health. Thanks for this great lecture!
My older sibling had bad asthma but they took up hiking-type activities in wild, natural areas, getting close to the soil, etc. Now they have no more need of Ventolin puffers. They also eat a very varied diet rich in pickles and other fermented foods. I think it helped their condition. Do you get out in nature at all?
I have eosinophilic asthma. Life ending level before the chemotherapy. Also an MD. The fermented food comment below is dead on- spicy pickle chips are a staple. I started hiking every week, 5-12 miles on a weekend, plus 2-4 miles a day on a treadmill, eating a plant/protein based diet and lung damaged has reversed over several years. Still some problems mid fev1 due to mid size bronchi, which responds to steroid inhaler and bronchodilators.
we follow a low pufa eating regiem with whole foods. We are using red light therapy to improve mitochondria response. We are seeing significant improvement in asthma. Hope this helps
Seek healthier, thicker, more supple cells in your lungs. When unhealthy thin and brittle irritants easily breech the cell lining. Then bodies natural response is histamine to flush irritants. If root issue not addressed then problem becomes chronic. Decrease any and all oxidative sources. Inhailants, preservatives, pesticides, etc. Eat more antioxidants. Fresh ripe fruits, berries are best.
@@Dblue-rhino Black seed oil is great for asthma...
Wow. What a speaker she is. I watched this video 4 times and got answers to many of my questions about gut microbiome. Thank you for sharing.
Simply fascinating! As a biomedical PhD student working on the Gut-Liver axis, the gut microbiome is extremely relevant for my research. I'm glad I convinced my PI to include a segment of experiments to check how the gut bacteria play a role in our models. Great things will come from microbiome research! It's still early days to come up with targeted therapies, but man, this is exciting research!
@Chrissie's Art Space Nice! There must and will be a link with epigenetics! Sounds so fascinating too! :D
A simple evolutionary question “ how would you like your digestive system to behave as your first line of defence and also as the necessary tool for metabolism” ? The quest for protection and maintenance. It all start with our first line of defence. Our “ first responders”, the gut
@@Urukanguro Nicely stated!
Chrissie's Art Space and Biomed Master sittiing in a tree! Get together and make research a treat! It's always great to meet people who are like us....
@@GLN14659 true that!
I am highly impressed ! Microbiome Science is in it's very beginning stage and has the enormous potential for application in treatment of ALL medical conditions. They are a true biomarkers of most deseases. I am full of admiration for Dr. Lynch for linking different ailments with different Microbiome diversity. These studies might be awarded with the Noble Price. It is already revolutionizing diagnostics.
vacciine damage the gut flora at very young age.--sickness leads new patients for big pharma. corruption
Exactly! One minor thing, and hardly worth mentioning, but here goes ... it's the "Nobel" Prize.
What a pleasure to hear that proactive scientists are unraveling so many causes and interactions in our own body ecosystem. 👏
Diet works to address inflammation. I’ve been a private health chef for 30 years and have seen positive results in 99% of my clients in their health journey.
What type of diet
Would you send me a message. I'm interested in doing this for others. I've been dealing with health issues for many years and understand diet can change peoples lives.
It's so funny cos my sisters boyfriend (who has Colitis) reckons the doctor told them to 'not eat highly fibrous foods as their body cannot break it down and they should stick to refined stuff'. Goes to show a lot of doctors don't learn about nutrition and are just taught to prescribe drugs!
and? did he eat fibre? what happened up till now?
Colitis help=seabuckthorn berry supplement (sea buck wonders is good) a miracle
Colitis is a specific physical disease, that requires a specific diet. Please educate yourself on why the doctor would have told him this, instead of making broad statements that essentially show you don't know what you're talking about and you just have an agenda that you would like to spout.
The reason the doc said that is because its true, in diseases where leaky gut has caused the gut to be badly damaged you cannot digest fibre and it causes more inflammation. The patient needs a strict elimination diet, like the specific carbohydrate diet, which allows the gut to heal and pinpoint specific foods which the patient has intolerance of whilst eating A multi strain Pro biotic lactose free yoghurt plus a fermented food daily.
If you lose the carpet of healthy gut bacteria, you are unable to absorb the byproducts of fibre digestion, hence developing colitis and diarrhoea. The doctor was completely correct in telling your sister's boyfriend that.
Dr Lynch and staff.... Thank you. I will be following your research. The amount of human suffering that potentially will be avoided is unfathomable. Thank you.
I would love to see a study about how stress affects the microbiome
@@ExistenceUniversity indeed.
I’ve read some good ones on meditation changing the microbiome for the better.
For over a month I've been preparing home made keffeir a glass intially each day, now every second day. I include a healthy Mediterranean diet and I can't believe how much better I feel . This is good research presented by the lady. Thank you from Australia 🙌
Stellar presentation of a fascinating frontier of medicine. Kudos and many thanks!!
This is a little long but I think it’s kind of interesting. I was a 4oyr old nurse that had naturally been thin all my life. I could eat all I wanted and did. I was a formula feed baby. I was brought up an a meat and potatoes diet. We always has a meat (beef, pork mostly, and sometimes chichen, NO fish or NO seafood) so we always had a meat, a starch whether it was potatoes or rice, and a vegetable. I don’t remember there being any fruit in my house when I was a child. I even had a set of triplets and all the weight I had gained came right off at age 33. However, everything changed when I was 37. I have breast cancer and needed surgery and 3 different chemo medications over 4 months. I pretty much made it through okay. But come about 1 1/2 - 2 years later I started to blow up like a balloon. I was gaining weigh so fast that sometimes my abdomen ached. I couldn’t stop it. I couldn’t eat as much as a used to eat and I started eating very little but still the weigh kept coming. It hit my belly first convincing everyone around me that I was pregnant. I was not. My doctor looked for tumors or cysts like on an ovary and there was none. Just fat. I know had a fatty liver and I don’t drink. The weight still kept coming. I went from weighing 125 lbs to 200 lbs over a few years. I have been at 200 lbs for probably 4 years now. I’m currently 50. But my weight still creeps up. I will look at the scale and I will be 210 lbs and then I have to starve to death to try to get back down to 200. I have tried dieting but I get sick when I down eat. Meaning my stomach hurts, I get a headache, and I’m nauseous. So instead a try eating just a small portion of food but that only holds me at this weight, Here’s the interesting part and this is all guess work on my part. This is all so new my doctors think I crazy. Remember that I am a nurse. My specialty is working with diabetics. Almost of of them are type II which is the one associated with obesity. My glucose level has been steadily raising and I now had pre-diabetes. No doubt to become full on type ii diabetes. I had 21 patiences a day and I worked a lot of hours. If you’re thinking many diabetic nurses are thin you are probably right but there are a lot of fat ones too. Here’s what’s different in my case. I had my gut biome completely destroyed by chemo therapy. One week before I started chemo I had some kind of skin infection so the doctor gave me everything under the sun that would kill whatever was affecting my skin. I had strong full spectrum antibiotics, anti-virus medicates and I don’t remember what else. So for the week prior to starting chemotherapy I had already given my gut biome a good killing. Then for four straight months, death to my gut biome. Going back to my job. I always eat the same foods that these people eat because I never brought my lunch so i would just steal the extra trays of food. I was very up close and physical with all these patients while taking care of there missing limbs, wounds that wouldn’t heal, and all kind of diabetes ii problems they had. At times I would have to use the main bathroom where many patients also used although they were supposed to use their bathrooms in their room. I know my microbiome was pretty much wiped out. The chemo also wipes out and reeks havoc with your immune system. I think as my biome was replacing itself it did it just like when you are a child. It got it from my environment and that happen to be a diabetes ward with a bunch of obese patients and their families. I think a fecal transplant but there’s not a lot doing obesity. Most are already full. And beside I live on the gulf side of Florida. And the weigh transplants aren’t near me. Another problem is that nobody takes me seriously. My story could be a possibility. It’s not impossible that it happened sort of like this. One good thing came out of chemo. Before chemo I had restless leg syndrome so bad most nights that I would cry because i was frustrated and it hurts. It would go on so long that eventually I would be so exhausted I would fall asleep for a little while. Well, guess what’s gone for almost a decade and a half? Yep, RLS completely gone. I think that is due to the destruction that chemo therapy does to your nerve or maybe it’s an unknown virus. I have no idea but I am so glad it’s gone. I wish I could tell this to a chief researcher of RLS. It might just be a fluke or maybe it could give them a clue.
I read about a case where a healthy (but overweight) person donated a fecal sample to a skinny (but sickly) woman. The sickly woman's colon problems were completely healed but she became overweight (just like her fecal donor) even though she had never been overweight before. I hope you are able to heal yourself. Good luck! : )
I would definitely recommend going plant-based (doesn't have to be full vegan) to build up your microbiome. Fruits, vegetables, fermented foods, sourdough etc.
Oh, and eat nuts.
Kate please look at Dr William Davis Making yoghurt, ( wheatbelly )shows how he made a yoghurt from a specific probiotic to boost gut bacteria and the benefits are amazing. Good bless you. my wife has cancer it's not easy,
Google how to make L. Reuteri yogurt. It will give you the recipe to boost your gut bacteria in your upper gi tract.
I would like to hear this professor's assessment of glyphosate, the ingredient in the herbicide Round Up. It kills the bacteria in our gut, on a daily basis. This is a call for the practical knowledge of this expert.
Sulfite intake is directly linked to asthma symptoms and urticaria. Sulfites are ubiquitous, as they are used as a fumigant, antimicrobial agent and bleaching agent in the manufacturing/processing of foodstuffs. In the U.S. ingredients of ingredients are not required to be listed on food labels. So you won’t see sulfites listed when they are used in the processing of food raw materials. The worst offender is high fructose corn syrup (HFCS). Sulfites are used as antimicrobial “preservatives” in high fructose corn syrup at 1000 times the level permitted by the FDA as an additive, but as an ingredient of an ingredient, it need not be disclosed. Compounding this problem is the fact that many pediatricians tell parents of asthmatic children to replace milk with juice - often containing high fructose corn syrup, thus heavily laden with sulfites. Sulfites are also used as a bleaching agent in regular sugar, flour and salt. So condiments and gravy and other flour products can be a problem. Sulfites are also used in the manufacturing process of all alcoholic beverages and all sugared beverages. Additionally, sulfites are found in all frozen seafood, to prevent black spots. The food technology industry has been allowed to become insidious in renaming high fructose corn syrup and even changing the manufacturing process, making it more potent and requiring more sulfites. There is information available on the internet regarding the tested content of sulfites in foodstuffs and the renaming of HFCS. If you, or someone you know suffer from asthma it’s worth the effort to research. Most of this information regarding sulfites became known because previously, restaurants were allowed to sprinkle metabisulfite on salad bar foods, e.g., greens, veggies, fruit, etc., resulting in more than a few asthmatics having immediate lethal asthma attacks. HTH!
Dr. Robert Martindale an expert in this field speaks of it.
@@wendyvan6818 yep this is the key...I'm a chemist, the sulfites have negative charge, they bind up the oxygen in your blood, thus the asthmatic attack...much like Red Tide here in Florida, the sulphur binds the oxygen in the water and suffocates the fish...sulfites are in wine, olives, shell fish and many processed foods, watch out for Nitrates in meat and phosphates in soda...good post
An amazing lecture! Finally, we are starting to focus on human studies confirming what already seen in animal models. Great results, and much more promising ones to come!
What an amazing lecture. I wish that every student of biology can watch these and understand the importance of quality lectures which have a true potential of provoking a genuine interest among students. Simply amazing!
Pbada, is that u? Pbadaaaa
Thankfully there are still excellent scientists and engineers and even technicians still in the World.
Here and there
⁴⁴⁴⁴try;
@oldrin old Just have to counter the evil/malicious with eternal life, the truth and that perpetuity known not so commonly as love. Most think love is lust or liking. No way is that my truth or spirit. Love is for the perpetuity of truth and life spirit and acts.
This was before the pandemic
Hi
In Ayurveda, we hold these 2 principles. First is to increase and fortify digestion; then 2, reduce and eliminate what is called Ama, undigested food particles and what is also considered pathologic mucus. Science confirms and elaborates on these principles. Eg., Ginger is useful to do both these functions. Re making a baby, I strongly suggest we study Ayurvedic principles, so we don't re-invent the wheel, so to speak. Most of us have forgotten how to make a healthy baby. Our study of Ayurveda and/or TCM can be our homework and we can prevent doctor visits that may not work in our favor. Wishing everyone good health. Thanx for your deep work.
Ginger is amazing.
Love your video and I totally get it. I’m 74 and really work at eating good/properly. Last, in the past I was obese and I realized I had to do life different now I’m improving in ALL areas all the time.
This was a terrific discussion. An informative and thorough explanation of the importance of a healthy and diversified gut microbiome; Specifically in the early stages of life.
This was fascinating. Thanks for making it understandable for lay people. I hope I get to see the healthy world humans could make with this science.
Great lecture! Can you test the influence of VACCINES in the microbiomes in early years? New borns until 10 yrs of age? How about on the elderly? This soooo much needed!
See Children's Health Defense dot org. Vaccines injure your immune system.
Dylanna Enzo Thank you for sharing this. I know the movement and Kennedy’s efforts. But if a University can study the human microbiome and effects of vaccines and report it, I bet the truth will not be hidden anymore.
Yes! !!!
I would also love to see studies on this
Great video. I have been educating my clients on this for the last 20 years. It's SUPER important. I have been taking HSO probiotic supplements and eating fermented foods my entire adult life. And I avoid antibiotic, antibacterial soap and hand sanitizers like the plague. Because I protect my microbiome at all costs!
Amazing lecture! Amazing story! Amazing people! I was amazed by the way she conveyed! Easy to understand! I'm glad youtube suggest this lecture!
Glad you liked it!
Magdalena..... my thoughts exactly. 😊
I agree. Absolutely fascinating topic and well presented.
@@openmind8620 hi
Breakthrough for the next generation So profound They are new every morning Ty
This is truly the best presentation I've heard on the subject, this far. It also scores high, as far as I'm concerned-- as far as "easy listening" as well!
This is one of the very best and the most accurate informative lecture on HEALTH for the 21st century. Thank you UC
Great informative lecture again making the case of the importance of gut microbiome in health and disease.
I was a 60s breast fed baby , 9 of 10 children. Playing in the dirt was a daily event. Had the mumps in kindergarten but never lost a day of school after that. Throughout my 62 years i have only been down to illness a small handful of times that lasted a week or more. I have always put my good health to consuming much citrus (vitamin c).
Health is so much more than intake of the most abundant vitamin, though. Eating whole, unprocessed foods, intermittent fasting, building muscle & doing cardio frequently each day, quality sleep, getting sunlight, stress reduction, good relationships, enjoying your job. Now THAT is summation.
I'm blown away by this.
Fascinating and well presented. It would be great to see some controlled studies on the health effects of fasting and time-restricted eating, both of which eliminated my chronic atopic dermatitis. No doctor had helped me before that, or suggested a link between my gut and my skin. Of course, fasting and eating fewer meals are free, so probably a hard sell.
That‘s so great to hear, good job! I had pretty significant skin issues in early childhood before my body really started rebelling after leaving Highschool (severe pains, digestive issues, anxiety, etc.). For me it seems the cause was a mix of stress, poor diet and microbiome issues (C-section, antibiotics). So I am in the process of healing up those issues with a healthy diet, light intermittent fasting and soon a microbiome transplant. Fascinating stuff.
@@gesund_mit_chris_IG Best wishes to you on your journey to better health. Keep us updated.
I started making my own bacteria. They suggest taking feces from a healthy person to transfer to another person. That is backward thinking to me. Probiotics are not enough in pill form for me. I started making things with kefir grains, yogurt, and I only eat smoothies with fiber and tons of bacteria that help me. I just usually use almond milk and I use a small amountwith regular milk introduced with kefir, probiotic pills, and yogurt. I will use just sugar water for bacteria to grow it. It tastes great. It is water kefir pretty much.
@@gesund_mit_chris_IG i wonder why as a muslims we are prescribed one full month fasting
Luann rouff... maybe if you try autohemotherapy. (without ozone) it is very good therapy for all kind skin problems. Guaranteed 100%
I'm a layperson so not the best judge of scientific info. I think this is a great presentation. I already knew tooth decay microbes are passed from mother to child but this is so much more than that. It makes sense microbes effect so many things. Fascinating! Thanks for uploading this. Keep this kind of info coming. Every person should know this stuff. Microbes effect everything in our lives.
Wonderful! *Susan Lynch is a great communicator. Thank you.
I do yearly coloscopy for colitis and not once has the Dr inquired about what I eat or whether I'm stressed.
Because if you change your diet and heal the doctor doesn’t make any money. Sad.
@@joycewright5386 Agree.
Excellent lecture! The best talk I have ever listened about the human microbiome.
An extraordinary lecture . The future of medicine starts from the gut .It must be placed left ,right and center. It is the only way to make sense of all systems in an evolutionary manner . Where we come from and where we are going
We are nothing but machines designed to be a vehicle for bacteria to spread across the world ;)
@@olereidar also a host for viruses to exist!
Alvaro, medicine will not change to NO HARMFUL MEDS anymore, no money to be made! Meds and processed foods for the labrats, that's all human kind is to the ones on the "top".
This not a new concept. There are Drs around the world who have worked in healing people by looking at the Gut as the source of problems first and foremost years ago. Humans are host to all forms of microbes. Its their interaction with us via the bowl that has to be the major priority in managing illness . Theres no way things will change because the simple truth is no money will be made from curing us from diseases like Diabetes, Heart, etc. The money is in medication.
@@olereidar you might be... I am not "just a machine"
SMH.. She said Aspartame kills off good gut bacteria and raises insulin more than glucose!! I spent my whole youth eating and drinking the stuff, no wonder I developed fatty liver disease and dysbiosis. On a side note, my mother's first child, conceived after she had been on the pill (which is known to affect the mother's microbiome), was kept impossibly clean and changed/bathed often. As the second child, I was allowed to be dirtier and also made to sit in dirty nappies for longer. I also got breastfed for a little longer than my older sibling. They grew up with severe constipation, constant colds/flu and illnesses and developed asthma and chronic obesity in childhood, while I didn't. It sounds like she's onto something.
Dr Lynch wow what an amazing topic!! enjoyed the video and look forward to see more of such. Thank you
Fantastic presentation. Incredible new field of studies. You're doing us proud over there Susan 🇮🇪
I just discovered this channel. Thank you and thank you.
Master class! Authoritative lecture for 80 minutes! Thank you!
Well if we do what the bible say all us will be well the bible tell us what to eat and what not to eat to stay well......Jesus did say we are hard headed and stiff neck lol.
And I'm not a Christian lol I use to be not no more I do believe there's a Spirit that created the universe that's for sure but not Christianity god smh.
One thing I'm disappointed in is that they ignored the Round Up widespread in the food supply, which destroys soil bacteria, and our food normally picks up soil microbes and that's how we normally inoculate our guts, from the food.
That's because Round Up is an herbicide, it has zero effect on bacteria. Please stop spreading internet rumors and look at scientific data.
Having said that, there's scientific evidence that Round Up might cause cancer in humans.
@@jefflebowski918 Sorry Jeff but the evidence clearly shows that glyphosate DOES affect the microbiota. Do a quick google search, it's scary. Please stop spreading industry propaganda.
Round-Up....brought to you by “MonSatan.” I hope Monsanto and all their employees go to hell..!
@@jefflebowski918 wrong
Thank you so much for sharing your knowledge
Wow that was eye opening. A pleasure to hear such a competent speaker on such an important and so far not explored far enough topic...
Super interesting. Just came into my feed. Couldn't stop listening.
AMAZING and Mesmerizing !!!! I watched it once and should watch it few times more....Thanks for such valuable information and research ....
Grateful for you and your work Dr. Lynch. Now more than ever it is key to eat SPECIFICALLY for our microbiome. We are what our microbes eat. If you happen to be afforded the luxury of having full autonomy over a two inch nutrient intake valve on the front of your skull USE it. It helps me to visualize how much area a goalie is responsible for in football. I just have to cover two inches. Trust me, you can do this!
I'm going to add that to my "No-No Diet" No Sugar, No salt, much less fat.
Round up. Very important to speak of this in the microbial world.
The research presentation was superb and results were directing different paths. Thanks to God . Everything is interrelated in this world.
I am so thankful I can learn from you on this channel. You're awesome!!!. Following.
Yes, great info, Thank you. But no mention of herbicides making their way into the natural food chain. And how this effects the microbiome of the parents and or the infant.
GMO’s and GLYPHOSATE wreck havoc on the gut microbiome through the bacteria SHIKAMATE pathway,The late Árpád Pusztai’s work on GMO’s is a must read for anyone interested in the gut microbiome
Yes, this should be a part of this discussion.
Ein sehr wichtiger Vortrag für die Gewinnung unseres wiederzuentdeckenden Selbstverständnisses ! -Thanks by the german "Lights"
She is really an efficient lady explaining the ecological niches of microbes...
Big pharmaceutical companies will not like this.
Big Pharma will own our microbiology 😡
If they don't they will squash this
Or the Dr's that are fo lazy to spend time with patients they rather u take a meds instead of educating patients...u r right!
This is a fantastic theoretical concept because it shifts the focus from siloed systems thinking to big data topigraphical data of small organism within their natural habitat than Petri dishes.
You are amazingly educated, full of much necessary information, however my little brain needs a simplified picture, then I can hear this again and it will allow me to understand fully or I can, listen to your phenomenal lecture. It is so marvelous. Ty
This presentation did a wonderful job explaining the microbiome. Dr. Lynch is obviously an expert in the field of the microbiome yet she fails to recognize the one thing that alters it the most, diet. I suffer from ulcerative colitis and am able to manage my disease by eating a diet that optimizes my biome. This could be another aspect to incorporate into your research as I think it is the most important part of the gut microbiota. Thanks!
Wow. Interesting stuff. The development of this research is critical. Keep up the good work.
thank you for sharing all this!!!
A great lecture on microbiota and its impact on human health and disease. Thank you.I.Venkateswarlu
I am interested in what the future of treatment is going to look like based on these discoveries. Great execution, thank you.
Excellent information. In our Indian traditional Ayurved system, much more stress is given on the food and digestive system. It emphasizes on the right food for keeping body healthy. Specifically more stress is on probiotics.
What are the probiotics used in traditional Ayurveda
Thanks for your service. We humans need your help thanks agin. You and your team are probably studying the most important part of our. Existence
Thank you so much. What an amazing presentation and so well articulated. You are awesome.
Excellent presentation! Very educational , thank you very much
Fascinating...and exciting. Really helps me increase my understanding of a whole range of subjects related to the roots of disease and common disorders.
The most up to to date and informative lecture about true human health ever,thank you,I wonder if biophoton's tie in with this somehow.
Ohh man I’m so glad I came across this post . I have some sort of circulatory inflammatory problem I’m hoping this can help
Need some poop?
You are a genius and u r gunna save my life, thank u for caring enough rhen the four Dr's I am seeing....im going to watch this every day and im gunna challenge my Dr's to watch this
Been plant based over 4 years. Definitely not going back. Stronger than ever, healthier than ever before.
This really lays the foundation of disease genesis to reside firmly in the gut! An excellent presentation and one which should form the basis for future study into this fascinating science.
Wow! What a lucid presentation! Kudos Dr Lynch!
Dr sahab pls tell something to us also... weak in English ... which Practically can be adopted
Great information,great lector,great future vision,great help for the future medicine policymakers.Thanx.
i involved in a competition in Hungary in the sixties while in collage and the second competition were about the evolution of the micro bacteria on the earth rom the beginning .... It was both interesting DEEP and DIFFICULT.
Thank you for the video. Clear and comprehensible presentation . I hope people stop using toxic pharmaceuticals and return to using phagocytes . Nurses in Georgia, USSR did a lot of work in this field. They drink deeply from the Pierian Spring.
The tools for understanding are also the tools for misunderstanding. Natural systems are complex super dynamic interdependent scenarios, a bit beyond our comprehension, but not our facilitation and participation, so long as we can curb our misunderstandings. Thanks for the excellent information!
Professor Susan Lynch is obviously such a smart lady and doing very important work. I am very much impressed.
Thank you for your research, Dr Susan Lynch on gut micro biome perturbation (23:00) - psoriasis, obesity, depression linking neurological and cardiovascular diseases. I’ve always suspected it was microbial. And your humour! That the gut isn’t like Vegas!!! 😂❤ thank you! I hope to interview you for my podcast, “Help! I’m prediabetic” .
It's good that she says clearly that this isn't the answer to everyone's problems. A word of note, my wife and I have a virtually identical diet, and where mine was always quite good and and balanced hers was very meat centric until I came along. Also I am way more athletic than she ever was. Now in the twilight of our lives I've had serious cardiac events and high blood pressure and struggle with my weight but no diabetes and she is as slim as the day I met her with low blood pressure and no sign of heart disease yet pre diabetes. This shows that the equation is extremely complex, and well beyond this very interesting presentation. What is need is an "overlord" that looks at this and the many other research projects going on and "filters" the content.
I saw a similar example with my parents. My dad jogged six miles a day, he played sports in college, never smoked. Mom had type 2 diabetes, smoked most of her life, stopped at 70 y/o. Her diet was terrible, sugary sodas, high simple carb diet. Mom outlived dad nearly a decade. As a dentist, I am realizing that root canal treatments on teeth can be a major cause of disease. I have read three great books on the subject, start with ''The Root Canal Coverup", by Meinig.
In fact, seems you are saying what Dr Lynch says in a section of this video, in other words. Yours distort what she said, in a slight way, but still you haven’t laid by kind of scientific golden egg here. Additionslly, what you provide as “proof” is a mini study comprising of only two people. Therefore, it’s not a scientific study. It’s what most people mistake for a scientific study; it’s simply a subjectively reported experience of 2 people. That being said, it also reinforces precisely what Dr Lynch reported in this video: the differences in generic microbiome, and it’s effects. (Or maybe I am bringing in parts of Dr Lustig’s video?)
@@dfinite4089 I make no claim of my "results" being scientific, only that they are accurate. I don't intend to distort what she says. As to differences in micro biome, the differences in the way the "shit stinks differently" for people in the same household for similar diet is testimony to that 🙂
So this just goes to show change your diet Change Your Life!! Wow. Now I know why my mother got rid of her asthma by changing her diet to a juice based diet and she had extremely bad asthma now she's thrown away her inhaler and can take a deep breath. It all starts from nutritious nutrition from the compost up🌱
Thanks for sharing! Yes we need to focus on our diets and not drugs. Happy for your mother. Smart woman!
Good video! Thanks for making this video available to the general public.
Genetics also play a role in some of the examples of diseases discussed. MTHFR deficiency gene mutations came to mind for example. As they say genes load the gun, environment pulls the trigger. Thanks- very interesting indeed. It looks like a good thing that some things seem to be improving when it comes to midwives learning about optimal cord clamping so that babies are getting a bit more of the blood that is essential for them at birth. ..and possibly for a healthier life. Some of the conditions mentioned can be found in the list of diseases common to those with MTHFR Deficiency gene mutations. Thank you for the work that you are doing. Mercury toxicity can be bad for immnune systems (often lymphocytes)( as well as most other systems in the body) and candida seems to like mercury and heavy metals..so these can affect gut flora quite seriously.
I loeved your presentation! Great and so important subject
We should really study people with “fibromyalgia” i.e. chronic widespread pain. I am certain it’s a condition caused by a disturbance in the gut microbiome. Curing these patients would get millions of people back to work, increase their QOL and save billions in healthcare spending.
Saving money on healthcare is, unfortunately not the real objective in the USA ... regardless of the rhetoric put forth in social discourse and politics about this aim.
I've heard fibromyalgia is an autoimmune disease so bacteria playing a role in causing it would make sense.
@Chrissie's Art Space thats wonderful! I have also changed my diet and fast frequently. I'm no longer suffering from constant widespread pain. I eliminated all grains and sugar from my diet and if I mess up just a little my body sure lets me know.
Every condition might be caused by a bad gut the beating of your heart might be gut related
@Chrissie's Art Space I too suffered for years with it among other health challenges! I changed my diet to a whole food unprocessed moderate to high fat moderate protein and low carb. I eliminated all grains from my diet and I am no longer in pain! I feel fantastic! I also don't consume soy corn canola or any veg oils and no sugars. Hbp gone! No meds fir conjestive heart failure and no more injections in my eye to keep me from going blind because of histoplasmosis! God is good!!
Thank you, very helpful. I'll put everything in practice. 🙏
Confirmation that the British gastroenterologist Andrew Wakefield was dead on when his small study suggested a correlation between the gut and autism.
They still won't admit vaccines are huge issue. Blame everything else!
@@JohnDoe-nz1eb never! sad!!
@PEMF iMRS You're right, it would cost billions in profits for pharma if everyone suddenly stopped vaccinating, but we don't need alternatives, as the totally unvaccinated are the healthiest segment of the population. Medicine won't admit that it doesn't know how to make safe and effective vaccines.
@PEMF iMRS Wow, sounds complicated. Think I'll stick to eating plants and let mother nature take care of the rest.
@@JohnDoe-nz1eb Yes & Read The Book Population Control Through Nuclear Pollution
Test on mice the changes on babies before birth? Also could changing the microbiome in older people be possible with fasting and reducing existing levels first. I had allergies and got rid of them after watching the science of fasting and fasted for 6 days, and how much more effective would it have been if I had these supplements while doing a long fast. Great info and thank you for sharing your findings with the community.
Indeed a nice presentation with lot of information about Microbiome. Thanks Susan Lynch and UCTV
Utterly fantastic research......HEALTH ....IT IS ALL IN THE GUT, ALL OF IT.
Great talk and clearly presented. While you made reference to natural birth and C-section in the early part of the talk it was not stated in the study looking at the three groups of babies for asthma whether these babies were all natural births. Can you clarify this? Also have you looked at the bacteria in the birth canal that the baby will pick up on it's way out in a natural birth and the importance of not cleaning the baby for as long as possible. (Is there a time factor here?). What do you think about the possibility that there is a connection between the microbiome and ALS, Alzheimer's etc. My background is in Mass Spec. Did you mean that pun at the end? "A large body is studying Obesity"
Wow all these processed packaged foods are killing the diversity of bacteria in our gut. No wonder we have so many food allergies and sensitivities
Kakapa
On top of the foods, we’ve got a LOT of pharmaceutical products going into the bodies of the nation.
The allergies and sensitivities are coming from the vaccines, primarily. Vaccines make the body atopic: a·top·ic /ˌāˈtäpik/ adjective denoting a form of allergy in which a hypersensitivity reaction such as dermatitis or asthma may occur in a part of the body not in contact with the allergen. Plus the vaccine media are made of many plant proteins. When the immune system is activated by the vaccine, the body sensitizes to the proteins in the blood.
Food pyramid is very bad...government is responsible for millions of deaths.
@@imstevemcqueen million of diseases specially in kids! Type1 diabetics, cancer, celiac disease, more and more!!! They are destroying our lives!!!!
Very professional reality Lecture. Much appreciated. Will help me widen my knowledge. I'm a clinical officer
Dr.Susan V Lynch gave a fantastic talk on Human Microbiome and she is well organised and concise in her delivery. Ever thought that the vaccines could have altered our microbiome? Children are getting more and more vaccines introduced to their body throughout their life. Could the vaccines perturbed the existing microbiome community? How many vaccines were given to children in the 50s compare to now? How about the prescription drugs?