Creating Synthetic Life | Kerstin Goepfrich | Escaped Sapiens #61

2024 ж. 19 Мам.
1 089 Рет қаралды

In this conversation I speak with Professor Kerstin Göpfrich, who works at Heidelberg University at the Center for Molecular Biology (ZMBH), and who is also leading the Max Planck Research Group for the Biophysical Engineering of Life.
Kerstin is attempting to construct living cells from scratch, piece by piece from non-living materials. So far she has created cell membranes, cytoskeletons, linkers for connecting cytoskeletons to the cell membrane, a mechanism for cell division, microscopic channels for ion transport in and out of cell membranes, an artificial 'mitochondria' analog, and more. The goal is eventually to put together all of these elements into a self replicating, and autonomous model 'cell'. We discuss her progress, and what it teaches us about the origins of life on earth. We also touch on the ethics of bringing an entirely new branch of life into existence.
►For more information about Kerstin's work see:
goepfrichgroup.de/kerstin-gop...
www.mr.mpg.de/person/53539/14...
These conversations are supported by the Andrea von Braun Foundation (www.avbstiftung.de/), as an exploration of the rich, exciting, connected, scientifically literate, and (most importantly) sustainable future of humanity. The views expressed in these episodes are my own and those of my guests.
The images used in this conversation were taken from:
-vesicle traffic 38;00 - Daniel von Wangenheim ( • fantastic vesicle traffic )
Smiley face 33;30 Paul W.K. Rothemund and Nick Papadakis
-DNA origami 32;00 - Dan Lou www.researchgate.net/publicat...
0:00 - 4 Creating synthetic life.
0:01:08 - What is life?
0:04:18 - Was life on earth inevitable?
0:07:22 - Why did life only start once?
0:11:11 - What is synthetic biology?
0:20:20 - The minimal steps to create synthetic life.
0:28:50 - DNA Origami.
0:37:00 - Building Cytoskeletons
0:41:31 - Programming form with DNA
0:52:18 - Creating dynamics.
1:00:50 - Autonomous movement.
1:03:20 - The story of mitochondria.
1:05:05 - Cell division
1:20:00 - What would a synthetic organism be like?
1:23:20 - When will we see synthetic life?
1:27:12 - Insight into the great filters.
1:30:00 - Natures greatest invention.
1:31:30 - Where are the aliens?
1:37:50 - Applications.
1:40:06 - Ethics of creating synthetic life.
1:49:00 - Biological infinity ship.
1:55:00 - Pharmaceuticals
1:59:40 - Being there when life is synthesized from the non-living
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Пікірлер
  • Great episode!

    @DaveShap@DaveShap6 ай бұрын
    • Cheers. Your avatar is fantastic btw :'D

      @EscapedSapiens@EscapedSapiens6 ай бұрын
  • I lover her, what a brilliant mind and beautiful extroverted willingness to share her knowledge

    @ArborProTriCities@ArborProTriCities5 ай бұрын
    • She is fantastic. Can't wait to see where her work develops.

      @EscapedSapiens@EscapedSapiens5 ай бұрын
  • Can you generate RNA with defined enzymatic activity or to function as an antibody?

    @JoseAntonioOU4@JoseAntonioOU422 күн бұрын
  • If it never dies, is there a need for replication for the definition of life?

    @JoseAntonioOU4@JoseAntonioOU422 күн бұрын
    • This... is a fantastic question. It makes me think of the Pando tree: en.wikipedia.org/wiki/Pando_(tree) I wonder if there is something out there that has forgotten how to replicate, but which simply endures at this point...

      @EscapedSapiens@EscapedSapiens22 күн бұрын
  • Micro-Frankenstein

    @Incantationem@Incantationem5 ай бұрын
  • You have to enhance your knowledge of morphogenic coding,,,,that is nature information or nature signature,,

    @mjbraj9517@mjbraj95176 ай бұрын
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