The Incredible Way This Jellyfish Goes Back in Time
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Patreon: / realscience
Twitter: / stephaniesamma
Instagram: / stephaniesammann
Credits:
Narrator/Writer: Stephanie Sammann
Writer: Angela Wipperman (www.angelawipperman.com)
Editor: Dylan Hennessy (www.behance.net/dylanhennessy1)
Illustrator/Animator: Kirtan Patel (kpatart.com/illustrations)
Animator: Mike Ridolfi (www.moboxgraphics.com/)
Sound: Graham Haerther (haerther.net)
Thumbnail: Simon Buckmaster ( / forgottentowel )
Producer: Brian McManus ( / realengineering )
Imagery courtesy of Getty Images
Additional Footage:
Sasuke Tsujita
Beni Jellyfish Regeneration Biology Experience Laboratory
Music:
Beyond by ANBR
Event Horizon by Charlie Ryan
When the Sunrise---instrumental-version by Yehezkel Raz
A Journeys Epilogue by Yehezkel Raz
Chachachill by Kola
References:
[1] thebiologist.rsb.org.uk/biolo...
[2] www.researchgate.net/publicat...
[3] www.nationalgeographic.com/an...
[4] pubmed.ncbi.nlm.nih.gov/29227...
[5] academic.oup.com/gbe/article/...
[6] www.nhm.ac.uk/discover/immort...
[7] repository.kulib.kyoto-u.ac.j...
[8] www.nytimes.com/2012/12/02/ma...
[9] www.ncbi.nlm.nih.gov/pmc/arti...
The Nebula and CuriosityStream deal is at an incredibly good price right now - $11.59 is an insanely good deal they are doing for Memorial Day! It won't be this cheap for very long so get in on it while the gettins good!
Awesome podcast BTW, please keep them coming 😊
hopefully someone invents a way to download memories, personality, cravings, and habits or the mind entirely to pair with jellyfish immortality (cloning?). Immortality without regression sounds kind of really far, unless robotics progresses enough Edit: Grammar and forgot a word or 2
please look up the documentary "A child Frozen in Time" could hold things as well..
@@shamelescampr5594 what about that monk who died while meditating but his body wouldn't decompose or decompose at a normal rate
Kill the dramatic music you psychopath
Epic, I will try this
Good luck mate!
Ok
Goodbye my brother may you reach you goal.
He can't reply, he's a polyp now
@@philipcarr5680 The SCP Foundation would like to know his current location
7:26 "And a bit like the plastic bits at the end of our shoelaces..." They're called aglets, there's an entire song about them.
I was trying to remember how old the song is. But on second thought I think I'd rather not know.
I guess she forgot about Aglets, a lot of people forgot about Aglets
@@1224chrisng could also be that even in the UK and former colonies, (minus America (and maybe India) because they have to be special) aglets is a pretty rare term, and outside of those countries it's basically unheard of.
@@mrjoe332 Actually, there's a song from Phineas and Ferb about them, not an old cartoon either
I only learned what they were called from Phineas and Ferb haha
It took 100 years after its discovery to realize the powers of this jellyfish. It might take another 100 years to implement the beneficial aspects of this.
Another 100 years for any benefits for us is optimistic.
And who knows what other animals we know of currently that may harbor incredible abilities!
our lifespans are fine how they are.
@@kinglil546 disagree
@@SickOfDemocracy you can disagree but it won’t make you right.
I love this channel so much, I started studying biology this semester and we just covered hydrozoa but in a way less interesring way. Its amazing how you can make the exact same topic that much more interesting
Show this to your teacher, and see if they become more or less interesting. If it's the latter, stop paying any fees and become a polyp
I did not learn anything that really counts about Quantum Mechanics and General Relativity when I studied Physics. KZhead videos told me the real story.
Schools are crap
Your instructors aren't focusing on simultaneously entertaining you.
God I love real science You guys have actually taught me a lot
@@robertsipe9748 I know lmao. It's supposed to be wierd liek dat
@pyropulse understandable Eucalyptus oil do be wildin
99% is just pure bullshit, relax!
I doubt very seriously God or any other "bieng" had anything to do with anything in the universe.
@@superdave54811 it... Was a joke.. But sure, I guess
It's hard to believe jellyfish and octopuses are from this planet. Evolution in the ocean seems to be so much more advanced than it is on land.
Is it really hard too tho? 75% of the planet is water. We are the ants in comparison my friend. What's out in the ocean is why beyond what humans will ever be as a whole, on this planet that is
@@RobsGravity yes it is and ok
Look at human
The alien creatures we share this planet with never ceases to blow my mind!
Not from a big bang obviously but from thought
These and octopus
If you know anything about the Metroid games, the metroids resemble cnidarians. I think the creators of the game thought the same.
"The slight inconvenience of death." Great line. I'm really enjoying your content. In depth, very well written, great narrative voice.
Hopefully one day we may be able to use something similar as a local treatment to fix a severed spine or other damaged tissues.
“Plastic bits on our shoelaces” Looks like somebody has never watched phineas and ferb
Some cartoon I'm guessing?
It's an aglet
Scrolled through the comments looking for this
6:21 Senescence is not cell death. On the contrary. It is living cells deteriorating in function and ceasing of cell division. They're rather accurately called "zombie cells" because they are indeed still active, just dysfunctional. They're still however releasing proinflammatory mediator chemicals, etc. (The so-called SASP, senescence-associated secretory phenotype).
I'll just sit back for a while and continue learning. Christ above, that's interesting
I'm so happy to read a comment like this, telomere biology is amazing btw
Yes! Apoptosis is the term for cell death, while senescence is what you just said. Senescent cells are cells with frayed telomeres!
@@dsakurai Not even necessarily. A cell can also become senescent with intact telomeres :)
@@Pyriphlegeton Then how could it be senescent if its DNA is functional?
I remember watching a documentary about a scientist in Japan that was obsessed with them, and how they may be the key for immortality in humans or much longer lifespans.
Not really
whats the link?
humans could never be immortal
@@kevinhurleyjr. You shouldnot say that
@@fly463 i already did
I think there's an overlooked aspect of the regression -- the polyp becomes multiple adults. This isn't one adult reverting to childhood and growing up again to refresh itself. This is an adult reproducing in a way that consumes itself. In an organism, over any given period of time, each cell has a chance of malfunctioning. Over time, these malfunctions accumulate until they threaten the life of the overall organism. In reproduction, a small number of cells are used to start a new organism. Fewer cells, fewer chances for malfunctions, lower chance of enough malfunctions accumulating to prevent the offspring from reaching maturity. If you sample enough conceptions that the number of starting cells is equal in number to the cells of an adult, you will be able to witness the chance malfunctions in the form of birth defects and nonviable larvae/fetuses/etc. But plenty of offspring did not experience those malfunctions, allowing the species to continue. In this regression-based reproduction, there may be a far greater number of old cells which will contribute to each new organism, meaning more defunct cells to start with and thus a reduced viability of each offspring. I'm interested to see if research has been done regarding that.
So are you basically saying that what the immortal jellyfish is doing is what we called Asexual Reproduction 40 years ago ???
@@cgrisby1965 the regression prior to the stress-reproduction is unique, and studying it definitely has the potential to improve medicine, buy it's far from immortality
@@klikkolee yes I agree that it's NOT Immortality, I was simply using the word immortal because I'm guessing it's part of it's name. NOTHING on Earth is immortal or incapable of death or destruction.
So basically like making a copy of a copy. Or a better analogy would be like using a plate to print. Every copy becomes less and less sharp than the original.
@@cgrisby1965 Nothing in the universe that we know of, not just the world.
It is always a treat when this channel produces new videos! Please keep them coming.
your layout for all your videos are amazing. You explain a little bit, then explain further with strong vocabulary and high res pics and good editing. Nice videos.
When literal eternal life isn't even the coolest thing you can do: sending yourself back in time is. Unbelievable creature.
You should do a video on the naked mole rat. It’s the only mammal that they’ve discovered that doesn’t age. They’ve also found that lobsters also don’t age. Maybe with a combination of Crisper CAS -9 and these animals we can find a way of extending human life.
That's a great idea
That's not really the case though, as lobsters certainly become more feeble and prone to illness with age. Aging is a much more complex process than just telomeres. As for naked mole rats, it might be said they age in a different way, or don't show signs of age the way other mammals do (even for the naked mole rat, their DNA shows signs of aging).
@@Ryodraco Agreed, if anything, the most fascinating thing about mole rats is that they're eusocial mammals.... like wasps and ants. Oh and they're nearly ectotherms. Weird creatures
extending human life sounds kind of unethical lol
@@sludgeskin depends on the person mate
It doesn't just roll back into a 'baby', it essentially turns back into a fetus. It's hard to consider this "immortality", it's arguably the same organism but once the babies spawn from the polyp it's certainly not the same individual. In a human, a process that could take us back that far would wipe clean all of the memories and scars that define a person's identity. You, as an individual human person, would slowly die as your brain shrunk and congealed into a mass of cells with no capacity for cognition. The resulting person(s) would essentially be a clone of the original. As she pointed out, that's not the purpose of the research, I'm just quibbling about how these creatures are commonly referred to as immortal. The research into telomeres could result in some kind of Lazarus treatment, but as pointed out in the video, in humans this would likely not result in us de-aging to such an extent. Most likely it would only "stop the clock" at our current age, but it could also potentially allow us to (very slowly) reverse the negative effects of aging to have the bone, neuron, and muscle resilience of a 30 year old.
Yeah, it could be something like: if your DNA is taken and a clone baby is created who looks just like you, then it wouldn't mean that it's you, in fact far from it, it will have different personality and will act differently than you... "You" isn't just your body, it also includes your feelings and consciousness which can't be simply added to your clone.
Another Paradoxical question that arises is that let's say a way is created by which you can make your own clone which has same consciousness, feelings and memories, as you have... does that mean it's really you? Like, is it really you or it's just your clone with your feelings and personality?
@@verytiredhonestly Jellies definitely bring up the question of where the boundaries of cognition, consciousness, and individuality are. They don't have brains, but they do have a complex, distributed nervous system capable of forming engrams. It can't be known whether these engrams are purely for motor memory, or they are capable of some level of experiential memory that could imply base level consciousness. There's more going on than flora that reflexively seek light, water, or rich soil. But less going on than more neurologically complex fauna capable of recognizing relatives and forming social bonds as individuals.
@@NTdredd This is the concept of 'continuity of consciousness', the idea that no mater how perfect and complete, a copy of you is not 'you'. In sci-fi t's often brought up in criticisms of the idea behind star-trek style teleporters, even by characters in the Trek universe who don't trust the technology.
That is essentially a biological "Ship of Theseus" discussion.
I really appreciate this series because there are not many cool biology related videos on this platform with this high quality
They literally go "reject maturity, return to polyp"
Now in 2022: You know your Jellyfish is imortal😂 Plastic in the ocean be like: ah i don't think so....you didn't see me coming.
Either i dont get the joke or you mistaken with sea turtles bro
Inspiring science, extraordinary editing and perfect narration! Just right, to watch with a cup of tea.
Wow, my thoughts exactly, and my tea is a green one, but it's too hot at the moment to enjoy
I appreciate the shopped photos/locally filmed footage and editing instead of stock footage
I love your channel! so detailed! keep up this good work.
So wouldn’t part of the key to unlocking this code be how does the jellyfish harness/control the enzymes that protect and reproduce telomeres?
I've always been interested in the immortal jellyfish.
same. The thought of being a jellyfish floating in the ocean is my calm place.
@@lauraanne5175 i ilike that. Now i don't know if I'm laughing in a good way
@@neanda 🌈
if other creatures eats it, it dies...nothing immortal
I'm obsessed with your channel. I love learning about different animals, especially aquatic animals.
I would love to do this, presuming these are light sensitive, split the groups into two tanks (or one per jelly), and flash lights red for a tested timeframe (say a day- so it's not too long or short), then some of the jellyfish a pinch to trigger it going back to polyp. The other is a control group of course. Then keep repeating this to see if the jellyfish starts reverting based on seeing the red light.
Wow this is so intriguing! Nature truly is such a wonderful thing 💕
Your voice is just perfect for these kind of videos
Wow, absolutely stunning information and as always perfectly made video. Thank you
Amazing, as always. Thank you!
Imagine how amazingly stellar the leap to immortality will (hopefully) be in the future of our species. Learning about this little creature is truly inspiring!
Amazing video! Excellent narration, fact finding and explanation on one of the most amazing animals on earth no doubt thank you.
It's things like this video, and your comment, that make me realise that all is not lost. Thank you
😊 😊 😊
😊
Yes! Her voice is everything!
Imagine existing like this for eternity, just existing, not knowing your in water..just existing in this environment…true hell
Absolutely amazing content. Greetings from Brazil!
What an incredible creature!
i found some of the lines so funny! like the shoelace tip, lunch with no content etc etc!
I love that you have the references!!!!! I actually want to read more about this
I literally learned more about biology right here than in my biology lessons. I like this channel
Truly fascinating 🎐
I love this channel so much. Thank you!
Thanks these vids are so well explained 👌
I feel as though my lifetime's worth of sci-fi stories have come to life lately...
I agree, I need more conspiracy theories because mine have all come true.
@Mary Morris Exactly! I'm thinking of watching some B-grade dystopian movies just to keep hope alive 😉
I would love to see a vocab list at the end btw, some might find it annoying, but I feel like I’d be able to remember more if the videos had this feature
Pausing and looking stuff up is what I do if I'm really into a subject.
Thank you for this!
Absolutely fascinating
Did you know the has avocado we eat technically comes from one single tree! This is true for a lot of stuff, you can find examples of negligible senescence everywhere but it's much less common in vertebrates.
Are you sure this is the case with avocados? While true for specific varieties that are reproduced through grafting, avocados produce genetically unique edible varieties from seed unlike some other fruits. There’s wild avocados everywhere where I live and they are all a little different. Every once and a while you can get a unique variety from seed that has desirable qualities and can then be grafted to other rootstocks. I seem to remember that the banana that we know and love was the result of a single genetic mutation though and we cultivate those as clones of the original varieties. For this reason many banana varieties are seriously at risk from the spread of diseases from which they cannot develop resistance to since they are all clones
@@maukaman I'm pretty sure it's true for the "Has" variety of avocado, that's why i specified, and yeah most commercially grown bananas are genetically identical.
Not only microRNA and telomere elongation, but gene silencing by chromatin condensation is very important in the aging process (probably causes the Second one). We need to shed more light on how the process works.
Gene slicing or silencing? 🤔because if you meant slicing.. we might have something huge hidden within the knowledge of jelly fish 🤯
Amazing video, gotta love this channel!
Great post my friend. Very fascinating abilities !! 🤩
Other animals: Oh no I'm gonna die 😢 Immortal Jellyfish: Ctrl + Z
Im excited to see what potential this knowledge and AI can produce for the human experience! What a time to be alive!!!
the writing in this episode was impeccable
Thanks for such an incredible video
i think the most interesting thing that could happen is life not being extended at all even if we physically retain our more youthful looks for longer so we just end up with 80 year Olds looking like 30 and 40 year olds.
Real Science literally became my science class
I love the way you say “Jellyfish”. It makes me feel younger.
I love all your videos and watch them every week.
Could this form of regeneration be considered a type of cloning- seeing as you end up with more, genetically identical (I assume) jellies?
I wonder if in the future we will find a way to synthesize telemorase and use it as a treatment to extend our lifespan
Well I’ve got good news and bad news for you! Good news, we can! Bad news… turns out giving cells extra telomerase can definitely make them cancerous 😅.
Well that's a big yikes lol
@@ashleyfarre Not if we can figure out to take out the side effects of that cancer I am guessing cause whales and larger animals do provide clues on how to stop cancer in their bodies.
Fantastic presentation. Very interesting and informative.
Real Science, please make a video on the insane biology of the Eel!!
It's crazy to think about how nature has all of the answers to our greatest questions. Or will eventually figure it out.
🤔
Fascinating! Nice content and presentation. This seems like a shortcut around nature's genetic blender though, and could lead to dead ends in the paths of evolution.
Not necessarily, because would it exist if you didn't know it could evolve?
@@neanda changes in allele frequencies in a population
This type of knowledge is absolutely groundbreaking and fascinating! what a beautiful video presentation of the information!
My Aunt passed to cancer almost 2 years ago, wish we had gotten more time with her and her grandkids together. Anything that helps us in the search for better means of treatment than chemo is valuable to explore. Thanks for creating wonderful content on an internet full of distractions.
Love it!!!!! Thanks for sharing!
I'm curious, could we use telomerase in some way to reverse damage to our own telomers?
Who came here after Miles told you about the immortal jellyfish?
Effective and intriguing presentation
The best and coolest animal ability. Deserve highest recognition among all animal
imagine it gets a lifetime prison amount
I heard a theory once that we lost the ability to regenerate telomeres as a defense against cancer (cancer cells can regenerate telomeres), is this jellyfish any more likely to get cancer?
*Grim reaper shows up* Jellyfish: I'm bout to ruin this mans whole career
this is the coolest thing ever!!!!!!
Your videos have such amazing production quality. It is always well presented and is a treat for curious folks. Keep up the good work. +1
Truly an amazing organism
Really awesome and promising field of research!
3:44 this is the generalized life cycle for scyphozoan jellies ("true jellyfish"), not for the hydrozoans, which Turritopsis belongs to. Turritopsis medusae develop as buds on the stalks of the polyp colony, and then detach as young medusae which resemble smaller versions of the mature medusae. They don't strobilate, i.e., divide via transverse divisions along the stalk of the polyp like is shown here, and they do not have an ephyra-like appearance as young medusae-the term "ephyra" is only used to describe young scyphozoan medusae.
Tbh , as a Zoology student i learnt more about animals from this channel than my textbooks lol😆
I think it's because textbook word things in unnecessarily convoluted way, whilst videos are often more colloquial. But yeah, this channel is a gem
@@ik6non712 yesyes agreed ...but also like .. In my country, the textbooks here are more focused on pushing knowledge into our brain, rather than creating a curious mind. So i think that plays a role too for growing intrest in a subject
@@swagatbaruah7839 Bro that happens everywhere. Try to get an internship so you get exposure to research methodology. Unless you go to a standard Institute, which is extremely tough in India, you will not get to have the advantage of both theory and research-oriented programmes. It takes effort, but internship at a good place will change the way you see your subject.
I love your work!
This is sooooooo coool. Kind of sent me into a trip for a second lmao
So we can use the jellyfishes telomerase to repair our telomeres? maybe we could have some kind of telomerase injections to boost telomere repairs
There is an atmospheric chamber therapy that regenerates our telomeres.
I would almost like the idea of immortality, if the universe itself he'll or our solar system and galaxy weren't going to die themselves and come to an end. It all seems pointless then. So maybe just a way to slow down aging, some sort of nanotechnology that can be created on a micro level to keep the telomeres elongated will work better for us.
love to watch your video it is very informative
Another really well done video :)
Scientists discover that living cells are machines and life is intelligently designed. It shouldnt have taken them so long.
Strength hair, Salt wife, Dragons, Talking donkey, Water wine, Water walkin, Resurrection, Virgin birth, Sight spit, 900 year old men, Sea splitting, Giants, Talking fire bush, Great flood, Talking snake, 3 day cruise in a huge fish belly, etc, etc. Go away.
@@goatrectum You will find out when you are cast away. Less than 1 zeptosecond after your death. Enjoy.
You'd think this designer would be smart enough to at least let us live longer. Maybe make us taller, not have to eat as much, something
@@arkkon2740 His intent is to emphasize the vanity and brevity of this life. The book of Ecclesiastes might interest you....
@@TheSharperSword Well whats the reason exactly? He created us and kinda forced us into existing, so whats even the point of giving your creations life if they dont want to live it sometimes?
Im convinced jellyfish aren’t from earth cause this is incredible
Maybe they are from Earth and we are the aliens.
Love the content. Enjoy the subtle use of humour. Grin every time you say "Brih-inn" ;)
Thank you for sharing us this amazing video I love them all 😍😍😍😍
When adulting gets hard..
Brb, let me crawl back in my mom's womb
I'm trying to find the comment about how all human... interaction ( not with nature) is all the same now , and then got diverted away from the comment which I later eventually realized( how could I not lol!) that too , was ANOTHER! ex about how there ..."technically" ....is no longer any surprises for me anymore lol! cuz THAT TOO .....was another behavior that has occured ...why ? .....hmmmmm....oh I know...CUZ I WAS TROLLED...IN....THE.... PAST! ....LOL! ..... Instead this time it was trolling seconds or min in THE PAST lol! ..... unlike the usual day, month, yr , or yrs ' ... type of trolling this time lol!
Let me crawl back up into my Petri dish!!! Hahaha 😂
I find this subject fascinating for life here on our little planet
5:05 - 9:05 the arpeggios in the background here were so pretty they kept distracting me from the actual video
How does a jellyfish taste like when cooked and eaten?
Only one way to find out ( ͡° ͜ʖ ͡°)
Absolutely nothing
@@Babigoldfish wait you're telling me you cooked and ate a jellyfish? Did it sting?
@@Zamu273 We use em in salads. Don’t like them at all cus they don’t even absorb the vinegar/nuoc mam sauce. We don’t eat poisonous ones obviously
@@Babigoldfish I thought Jellyfish produced jam?
Real Science lapel pins 🥺👉👈
omg. yes
Narrarator really knows how to advertise. I need something to binge watch
literally started watching this video for my lunch, what a sales pitch for the sponser.